Last updated — February 2026
Open Methodology
How Atlas Rare works:
Where the trial data comes from
ClinicalTrials.gov, updated in real time via their public API. Every recruiting trial in the US. We don’t curate or filter based on sponsor relationships.
How we match trials to you
Four stages: we expand your condition to include every clinical synonym. We hard-filter by age, sex, and recruiting status. We extract eligibility criteria using AI and compare them to your profile. We return only trials where you meet inclusion criteria or where exclusion criteria are unclear enough to discuss with your doctor.
What the AI does and doesn’t do
The AI reads eligibility text and compares it to your profile. It does not make medical decisions. It does not know your full medical history. It makes mistakes. Every match includes exactly why we matched it so you and your care team can evaluate it.
How often it updates
Trial data: weekly. Your profile: whenever you update it. Memory of your past searches: continuously.
What Basic Mode is
If you turn on Basic Mode in Settings, Atlas Rare uses no AI memory. Every session starts fresh. You get the same trial matching and research tools with no learning layer.
Who to contact with questions
This page is updated whenever our methodology changes. If something here doesn't match what you're experiencing, email us — we want to know.